PMS1 Antibody (CL14436) - Azide and BSA Free

Analysis in human cell line HEL.

• Reactivity: Hu
• Applications: WB
• Clone: CL14436
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: LYOPH

PMS1 Antibody (CL14436) - Azide and BSA Free Summary

• Immunogen: This antibody was generated using a synthetic peptide of P54277, with the exact immunogen sequence remaining proprietary.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: PMS1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1 ug/ml

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from a 0.2 um filtered solution in PBS with Trehalose
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein A purified
• Reconstitution Instructions: Centrifuge the vial of lyophilized antibody at 12,000 x g for 20 seconds. Reconstitute by adding sterile, distilled water to achieve a final antibody concentration of 1mg/ml.

Alternate Names for PMS1 Antibody (CL14436) - Azide and BSA Free

• DKFZp781M0253
• FLJ98259
• HNPCC3
• hPMS1
• human homolog of yeast mutL
• mismatch repair gene PMSL1
• PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
• PMS1 protein homolog 1
• PMSL1DNA mismatch repair protein PMS1
• postmeiotic segregation increased (S. cerevisiae) 1
• rhabdomyosarcoma antigen MU-RMS-40.10B
• rhabdomyosarcoma antigen MU-RMS-40.10E

Background

PMS1 was identified by its homology to a yeast protein involved in DNA mismatch repair. A role for this protein in mismatch repair has not been proven. However, the protein forms heterodimers with MLH1, a DNA mismatch repair protein, and some cases of hereditary nonpolyposis colorectal cancer have been found to have mutations in the gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PMS1