Plexin C1 Antibody (1A12) - Azide and BSA Free

ELISA: Plexin C1 Antibody (1A12) [H00010154-M06] - Detection limit for recombinant GST tagged PLXNC1 is approximately 1ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: ELISA
• Clone: 1A12
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

Plexin C1 Antibody (1A12) - Azide and BSA Free Summary

• Immunogen: PLXNC1 (NP_005752, 250 a.a. ~ 348 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. PYNYTSGAATGWPSMARIAQSTEVLFQGQASLDCGHGHPDGRRLLLSSSLVEALDVWAGVFSAAAGEGQERRSPTTTALCLFRMSEIQARAKRVSWDFK
• Specificity: PLXNC1 (1A12)
• Isotype: IgG2b Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: PLXNC1
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: Antibody reactive against recombinant protein on ELISA. GST alone used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Plexin C1 Antibody (1A12) - Azide and BSA Free

• CD232 antigen
• CD232
• plexin (semaphorin receptor)
• Plexin C1
• PLXNC1
• PLXN-C1
• receptor for viral semaphorin protein
• receptor for virally-encoded semaphorin
• VESPR
• VESPRplexin-C1
• Virus-encoded semaphorin protein receptor

Background

Plexin C1, also known by its gene name PLXNC1, is approximately 176kDa and 1,568 amino acids in length. Plexin C1 is localized to the cellular membrane as a transmembrane receptor for the Semaphorins family of proteins. Plexin C1 may be implicated in the regulation of melanocyte adhesion and may be a melanoma tumor suppressor. Current research on Plexin C1 is being performed in relation to several diseases and disorders including Parkinson's disease, leukemia, kidney disease, melanoma, smallpox, prostate cancer, malignant glioma, renal cell carcinoma, ovarian cancer, pancreatic cancer, hepatitis, prostatitis, and pancreatitis. Plexin C1 has also been shown to have interactions with SEMA7A in the axon guidance pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PLXNC1
• Entrez:
  • 10154(Human)
• OMIM:
  • 604259(Human)
• Uniprot:
  • NP_005752(Human)