Western blot shows lysates of mouse brain tissue. PVDF Membrane was probed with 2 µg/mL of Rat Anti-Mouse Plexin A2 Monoclonal Antibody (Catalog # MAB5486) followed by HRP-conjugated Anti-Rat IgG Secondary Antibody ...read more
Plexin A2 was detected in immersion fixed bEnd.3 mouse endothelioma cell line using Rat Anti-Mouse Plexin A2 Monoclonal Antibody (Catalog # MAB5486) at 10 µg/mL for 3 hours at room temperature. Cells were stained using ...read more
Plexin A2 was detected in immersion fixed HUVEC human umbilical vein endothelial cells using Rat Anti-Mouse Plexin A2 Monoclonal Antibody (Catalog # MAB5486) at 10 µg/mL for 3 hours at room temperature. Cells were ...read more
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Protein A or G purified from hybridoma culture supernatant
Reconstitute at 0.5 mg/mL in sterile PBS.
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Plexin A2 Antibody (583603)
OCTSemaphorin receptor OCT
transmembrane protein OCT
Plexin A2 (also OCT) is a 220-230 kDa member of the plexin-A subfamily,
plexin family of proteins. It is found on cerebellar granule cells,
sensory neurons, and cardiac neural crest cells. It participates in cell
migration and axon guidance, and does so by serving as a receptor for
Sema6A and B, and as a coreceptor with neuropilin-1 for Sema3A and C.
Mature mouse Plexin A2 is an 1860 amino acid (aa) type I transmembrane
glycoprotein. It contains a 1203 aa extracellular domain (ECD) and a 636
aa cytoplasmic region. The ECD contains one Sema domain (aa 35-508),
three PSI domains (aa 510-855) and four IPT regions (aa 858-1228). There
is one alternate start site 10 aa upstream of the standard start site.
Over aa 35-1237, mouse Plexin A2 shares 96% aa sequence identity with
human Plexin A2.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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