Western blot shows lysates of mouse brain tissue. PVDF Membrane was probed with 2 µg/mL of Rat Anti-Mouse Plexin A2 Monoclonal Antibody (Catalog # MAB5486) followed by HRP-conjugated Anti-Rat IgG Secondary Antibody ...read more
Plexin A2 was detected in immersion fixed bEnd.3 mouse endothelioma cell line using Rat Anti-Mouse Plexin A2 Monoclonal Antibody (Catalog # MAB5486) at 10 µg/mL for 3 hours at room temperature. Cells were stained using ...read more
Plexin A2 was detected in immersion fixed HUVEC human umbilical vein endothelial cells using Rat Anti-Mouse Plexin A2 Monoclonal Antibody (Catalog # MAB5486) at 10 µg/mL for 3 hours at room temperature. Cells were ...read more
Chinese hamster ovary cell line CHO-derived recombinant mouse Plexin A2 Met35-Pro1237 Accession # P70207
Specificity
Detects mouse Plexin A2 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human Plexin A4, B1, B2, D1, recombinant mouse Plexin A1, A3, B3, or C1 is observed.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Rat
Gene
PLXNA2
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Plexin A2 Antibody (583603) [Unconjugated]
FLJ11751
FLJ30634
KIAA0463plexin 2
OCT
OCTSemaphorin receptor OCT
Plexin A2
PLXN2
PLXN2plexin-A2
PLXNA2
transmembrane protein OCT
Background
Plexin A2 (also OCT) is a 220-230 kDa member of the plexin-A subfamily,
plexin family of proteins. It is found on cerebellar granule cells,
sensory neurons, and cardiac neural crest cells. It participates in cell
migration and axon guidance, and does so by serving as a receptor for
Sema6A and B, and as a coreceptor with neuropilin-1 for Sema3A and C.
Mature mouse Plexin A2 is an 1860 amino acid (aa) type I transmembrane
glycoprotein. It contains a 1203 aa extracellular domain (ECD) and a 636
aa cytoplasmic region. The ECD contains one Sema domain (aa 35-508),
three PSI domains (aa 510-855) and four IPT regions (aa 858-1228). There
is one alternate start site 10 aa upstream of the standard start site.
Over aa 35-1237, mouse Plexin A2 shares 96% aa sequence identity with
human Plexin A2.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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