PIKFyve/PIP5K3 Antibody - C-terminus

• Reactivity: Hu
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

PIKFyve/PIP5K3 Antibody - C-terminus Summary

• Immunogen: A synthetic peptide corresponding to the C-terminal region of human PI3K, type III protein.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PIKFYVE
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: This antibody is tested in ELISA and Western Blot. This antibody is useful in Immunohistochemistry. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~237kDa corresponding to the appropriate cell lysate or extract.

Reactivity Notes

BLAST analysis was used to suggest cross-reactivity with mouse and human based on 100% sequence homology. Cross-reactivity with PI3K, type III from other sources has not been determined.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 50% (v/v) Glycerol
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Alternate Names for PIKFyve/PIP5K3 Antibody - C-terminus

• 1-phosphatidylinositol-3-phosphate 5-kinase
• EC 2.7.1.150
• FAB1
• FLJ37746
• FYVE finger-containing phosphoinositide kinase
• KIAA0981CFD
• MGC40423
• p235
• Phosphatidylinositol-3-phosphate 5-kinase type III
• Phosphatidylinositol-3-phosphate 5-kinase
• phosphoinositide kinase, FYVE finger containing
• PIKFyve
• PIP5K
• PIP5K3
• PIP5K3FAB1
• PIPkin-III
• Type III PIP kinase
• type III

Background

PIP5K3 belongs to a large family of lipid kinases that alter the phosphorylation status of intracellular phosphatidylinositol. Signaling by phosphorylated species of phosphatidylinositol regulates diverse cellular processes, including membrane trafficking and cytoskeletal reorganization (Shisheva et al., 1999 [PubMed 9858586]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PIKFYVE