PI 3-Kinase p85 alpha Antibody (572106) [Alexa Fluor® 750]

• Applications: WB
• Clone: 572106
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 750

PI 3-Kinase p85 alpha Antibody (572106) [Alexa Fluor® 750] Summary

• Immunogen: E. coli-derived recombinant human PI 3-Kinase p85α
  aa Lys519-Gly644
  Accession # P27986
• Specificity: Detects human, mouse and rat PI 3-Kinase p85 alpha in Western blots.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

PI 3-Kinases phosphorylate the inositol ring on a variety of membrane-associated phosphatidylinositols. Class I phosphoinositide 3-kinases (PI 3-Kinases) are heterodimeric proteins that consist of a catalytic subunit of 110‑120 kDa and an associated regulatory subunit. p85 alpha is one of the regulatory subunits that associate with the class IA PI 3-Kinases. Composed of one SH3 and two SH2 domains, p85 alpha functions as an adaptor, coupling catalytic p110 to activated receptor tyrosine kinases.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.