PI 3-Kinase p85 alpha Products

Antibodies
PI 3-Kinase p85 alpha Antibod ...
PI 3-Kinase p85 alpha Antibody (6G10)
NBP2-22212
Species: Hu, Mu
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
PI 3-Kinase p85 alpha Antibod ...
PI 3-Kinase p85 alpha Antibody
NBP2-19815
Species: Hu, Mu, Rt, Bovine, Monkey
Applications: WB, IHC, IHC-P, IP
Host: Rabbit Polyclonal
PI 3-Kinase p85 alpha Antibod ...
PI 3-Kinase p85 alpha Antibody (3A10)
Species: Hu, Mu, Rt
Applications: WB, ELISA, IP, PLA
Host: Mouse Monoclonal
Antibody Pairs
PI 3-Kinase p85 alpha Antibod ...
PI 3-Kinase p85 alpha Antibody Pair
H00005295-PW1
Species: Hu
Applications: WB, IP
Lysates
PI 3-Kinase p85 alpha Overexp ...
PI 3-Kinase p85 alpha Overexpressi...
H00005295-T01
Species: Hu
Applications: WB
Proteins
PI 3-Kinase p85 alpha Recombi ...
PI 3-Kinase p85 alpha Recombinant ...
H00005295-P01
Species: Hu
Applications: WB, ELISA, PA
PI 3-Kinase p85 alpha Partial ...
PI 3-Kinase p85 alpha Partial Reco...
H00005295-Q01
Species: Hu
Applications: WB, ELISA, PA
PI 3-Kinase p85 alpha Recombi ...
PI 3-Kinase p85 alpha Recombinant ...
NBP1-89731PEP
Species: Hu
Applications: AC
RNAi
PI 3-Kinase p85 alpha RNAi
PI 3-Kinase p85 alpha RNAi
H00005295-R05
Species: Hu
Applications: RNAi, RNAi SP
PI 3-Kinase p85 alpha RNAi
PI 3-Kinase p85 alpha RNAi
H00005295-R06
Species: Hu
Applications: RNAi, RNAi SP
PI 3-Kinase p85 alpha RNAi
PI 3-Kinase p85 alpha RNAi
H00005295-R04
Species: Hu
Applications: RNAi, RNAi SP

Description

PI3-Kinases (PI3-Ks) are a family of lipid kinases that are implicated in signal transduction. PI3-K consists of two subunits; the regulatory subunit p85 and the catalytic subunit p110 (1-2). In quiescent cells p85 maintains p110 in a low activity state. Upon growth factor stimulation, p85 directly interacts with phosphotyrosine residues of activated growth factor receptors or adaptor proteins leading to activation of p110. p85 exists in two isoforms: p85, including two short forms termed p50 and p55/AS53 and p85 including short form p55PIK/p55 (3). The p85 adaptor protein uses the inter-SH2 (iSH2) region to bind p110 and employs SH3 and SH2 domains, phosphotyrosine residues, and proline-rich motifs to interact with activated tyrosine kinases such as BCR/ABL and NPM/ALK or adaptor proteins including Shc, c-Cbl, Crk-L, and Gab2 (4-5).

Bioinformatics

Entrez Human
Mouse
Mouse
Rat
Rat
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 5295
Alternate Names
  • phosphatidylinositol 3-kinase-associated p-85 alpha
  • PtdIns-3-kinase regulatory subunit p85-alpha
  • phosphatidylinositol 3-kinase, regulatory, 1
  • PtdIns-3-kinase regulatory subunit alpha
  • phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
  • Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha
  • phosphatidylinositol 3-kinase regulatory subunit alpha
  • p85-ALPHA
  • PI3K regulatory subunit alpha
  • p85
  • GRB1PI3-kinase subunit p85-alpha
  • PI3-kinase regulatory subunit alpha
  • phosphoinositide-3-kinase, regulatory subunit 1 (alpha)

Research Areas for PI 3-Kinase p85 alpha

Find related products by research area and learn more about each of the different research areas below.

Lipid and Metabolism
Phospho-Specific
Signal Transduction

PTMs for PI 3-Kinase p85 alpha

Learn more about PTMs related to PI 3-Kinase p85 alpha.

Phosphorylation
Methylation
Deacetylation

Bioinformatics Tool for PI 3-Kinase p85 alpha

Discover related pathways, diseases and genes to PI 3-Kinase p85 alpha. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.