PI 3-Kinase p110 gamma Antibody [PerCP]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: PerCP

PI 3-Kinase p110 gamma Antibody [PerCP] Summary

• Immunogen: E. coli-derived recombinant human PI 3‑Kinase p110 gamma
  Asn298-Leu467
  Accession # P48736
• Specificity: Detects human PI 3-Kinase p110 gamma in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: PIK3CG
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Alternate Names for PI 3-Kinase p110 gamma Antibody [PerCP]

• 1-phosphatidylinositol 3-kinase
• EC 2.7.1
• EC 2.7.1.153
• p110-gamma
• p120-PI3K
• phosphatidylinositol 3 kinase gamma, p110 gamma
• phosphatidylinositol 3-kinase catalytic 110-kD gamma
• phosphatidylinositol 3-kinase, catalytic, gamma polypeptide
• Phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma
• phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
• phosphoinositide-3-kinase gamma catalytic subunit
• phosphoinositide-3-kinase, catalytic, gamma polypeptide
• PI 3Kinase p110 gamma
• PI 3-Kinase p110 gamma
• PI3CG
• PI3K
• PI3K-gamma
• PI3Kgamma
• PI3K-gamma
• PI3-kinase subunit gamma
• PIK3
• PIK3CG
• PtdIns-3-kinase subunit gamma
• PtdIns-3-kinase subunit p110-gamma

Background

PI3-Kinases (PI3-Ks) are a family of lipid kinases that are implicated in signal transduction. PI3-K consists of two subunits; p85 and p10. The p85 subunit localize PI3-K activity to the plasma membrane while the p110 subunit contains the catalytic domain of PI3-K (1-2). Four isoforms of p110 has been found; alpha, beta, gamma, and the delta subunit (3). The gamma isoform is most clostly related to p110 alpha, and beta and has been shown not to interact with p85 in vivo (4). It has been found that in p110-gamma protein expression is lost in primary colorectal adeno-carcinomas and in colon cancer cell lines (5)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PIK3CG