PI 3-Kinase p110 gamma Products

Description

PI3-Kinases (PI3-Ks) are a family of lipid kinases that are implicated in signal transduction. PI3-K consists of two subunits; p85 and p10. The p85 subunit localize PI3-K activity to the plasma membrane while the p110 subunit contains the catalytic domain of PI3-K (1-2). Four isoforms of p110 has been found; alpha, beta, gamma, and the delta subunit (3). The gamma isoform is most clostly related to p110 alpha, and beta and has been shown not to interact with p85 in vivo (4). It has been found that in p110-gamma protein expression is lost in primary colorectal adeno-carcinomas and in colon cancer cell lines (5)

Bioinformatics

Entrez	30955 Mouse 5294 Human
Uniprot	AAH35683 Human NM_002649 Human NP_002640 Human NP_002640. Human P48736 Human
Product By Gene ID	5294
Alternate Names	1-phosphatidylinositol 3-kinase EC 2.7.1 EC 2.7.1.153 p110-gamma p120-PI3K phosphatidylinositol 3 kinase gamma, p110 gamma phosphatidylinositol 3-kinase catalytic 110-kD gamma phosphatidylinositol 3-kinase, catalytic, gamma polypeptide Phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform phosphoinositide-3-kinase gamma catalytic subunit phosphoinositide-3-kinase, catalytic, gamma polypeptide PI3CG PI3K PI3Kgamma PI3K-gamma PI3-kinase subunit gamma PIK3 PtdIns-3-kinase subunit gamma PtdIns-3-kinase subunit p110-gamma

Research Areas for PI 3-Kinase p110 gamma

Find related products by research area and learn more about each of the different research areas below.

mTOR Pathway
Phospho-Specific
Signal Transduction