PI 3-Kinase p110 gamma Products

Description

This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias.

Bioinformatics

Entrez	5294 Human
Uniprot	AAH35683 Human
Product By Gene ID	5294
Alternate Names	1-phosphatidylinositol 3-kinase EC 2.7.1 EC 2.7.1.153 p110-gamma p120-PI3K phosphatidylinositol 3 kinase gamma, p110 gamma phosphatidylinositol 3-kinase catalytic 110-kD gamma phosphatidylinositol 3-kinase, catalytic, gamma polypeptide Phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform phosphoinositide-3-kinase gamma catalytic subunit phosphoinositide-3-kinase, catalytic, gamma polypeptide PI 3Kinase p110 gamma PI 3-Kinase p110 gamma PI3CG PI3K PI3K-gamma PI3Kgamma PI3K-gamma PI3-kinase subunit gamma PIK3 PIK3CG PtdIns-3-kinase subunit gamma PtdIns-3-kinase subunit p110-gamma

Research Areas for PI 3-Kinase p110 gamma

Find related products by research area and learn more about each of the different research areas below.

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