PI 3-Kinase p110 delta Antibody (275144) [Alexa Fluor® 488]

• Applications: WB
• Clone: 275144
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

PI 3-Kinase p110 delta Antibody (275144) [Alexa Fluor® 488] Summary

• Immunogen: E. coli-derived recombinant human PI 3-Kinase p110δ
  Cys391-Phe542
  Accession # O00329
• Specificity: Detects endogenous human PI 3-kinase p110δ in Western blots.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

Class IA phosphoinositide 3-kinases (PI 3-kinases) are a family of p85/p110 heterodimeric lipid kinases that function as signal transducers downstream of growth factor receptors, mainly receptor tyrosine kinases. Mammals express three class IA catalytic subunits: p110 alpha , p110 beta , and p110δ. The p110δ subunit is expressed predominantly in leukocytes, indicating that it may play a role in immune signaling.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.