Phospholipid Scramblase 1/PLSCR1 Antibody (1F9)

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Sandwich ELISA: Phospholipid Scramblase 1/PLSCR1 Antibody (1F9) [H00005359-M01] - Detection limit for recombinant GST tagged PLSCR1 is approximately 3ng/ml as a capture antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Clone
1F9
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

Phospholipid Scramblase 1/PLSCR1 Antibody (1F9) Summary

Immunogen
PLSCR1 (AAH32718, 1 a.a. - 318 a.a.) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MDKQNSQMNASHPETNLPVGYPPQYPPTAFQGPPGYSGYPGPQVSYPPPPAGHSGPGPAGFPVPNQPVYNQPVYNQPVGAAGVPWMPAPQPPLNCPPGLEYLSQIDQILIHQQIKLLEVLTGFETNNKYEIKNSFGQRVYFAAEDTDCCTRNCCGPSRPFTLRIIDNMGQEVITLERPLRCSSCCCPCCLQEIEIQAPPGVPIGYVIQTWHPCLPKFTIQNEKREDVLKISGPCVVCSCCGDVDFEIKSLDEQCVVGKISKHWTGILREAFTDADNFGIQFPLDLDVKMKAVMIGACFLIDFMFFESTGSQEQKSGVW
Localization
Cell Membrane (single-pass type II membrane protein) and Nuclear.
Specificity
PLSCR1 - phospholipid scramblase 1
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
PLSCR1
Purity
IgG purified
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Applications/Dilutions

Dilutions
  • ELISA
Application Notes
Antibody reactivity against recombinant protein on ELISA.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Phospholipid Scramblase 1/PLSCR1 Antibody (1F9)

  • Erythrocyte phospholipid scramblase
  • MMTRA1B
  • MMTRA1BCa(2+)-dependent phospholipid scramblase 1
  • Phospholipid Scramblase 1
  • PL scramblase 1
  • PLSCR1

Background

Phospholipid scramblase 1 (PLSCR1) is a member of the PLSCR protein family. These proteins are ATP-independent lipid translocators localized to the plasma membrane and is involved in a calcium dependent, nonspecific and rapid redistribution (scrambling) of phospholipids when a perturbation of plasma membrane asymmetry is needed for the cell (e.g. following cell activation, injury, or apoptosis). The expression of PLSCR1 is found in a variety of tissue and can be stress-induced. Upon stimulation (e.g. interferon stimulation), a portion of newly synthesized PLSCR1 is imported into the nucleus (instead of inserted into the plasma membrane) and interacts with DNA, consistent with a role in gene regulation. PLSCR1 may be closely associated with the pathophysiology underlying infection and inflammation, which manifest marked changes in energy consumption and lipid metabolism.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PLSCR1
Entrez
OMIM
Uniprot