Phospholipid Scramblase 1/PLSCR1 Antibody (1F9) - Azide and BSA Free

Sandwich ELISA: Phospholipid Scramblase 1/PLSCR1 Antibody (1F9) [H00005359-M01] - Detection limit for recombinant GST tagged PLSCR1 is approximately 3ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: ELISA
• Clone: 1F9
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

Phospholipid Scramblase 1/PLSCR1 Antibody (1F9) - Azide and BSA Free Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: PLSCR1 (AAH32718, 1 a.a. ~ 318 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MDKQNSQMNASHPETNLPVGYPPQYPPTAFQGPPGYSGYPGPQVSYPPPPAGHSGPGPAGFPVPNQPVYNQPVYNQPVGAAGVPWMPAPQPPLNCPPGLEYLSQIDQILIHQQIKLLEVLTGFETNNKYEIKNSFGQRVYFAAEDTDCCTRNCCGPSRPFTLRIIDNMGQEVITLERPLRCSSCCCPCCLQEIEIQAPPGVPIGYVIQTWHPCLPKFTIQNEKREDVLKISGPCVVCSCCGDVDFEIKSLDEQCVVGKISKHWTGILREAFTDADNFGIQFPLDLDVKMKAVMIGACFLIDFMFFESTGSQEQKSGVW
• Localization: Cell Membrane (single-pass type II membrane protein) and Nuclear.
• Specificity: PLSCR1 - phospholipid scramblase 1
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: PLSCR1
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Sandwich ELISA
• Application Notes: Antibody reactivity against recombinant protein on ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Phospholipid Scramblase 1/PLSCR1 Antibody (1F9) - Azide and BSA Free

• Erythrocyte phospholipid scramblase
• MMTRA1B
• MMTRA1BCa(2+)-dependent phospholipid scramblase 1
• Phospholipid Scramblase 1
• PL scramblase 1
• PLSCR1

Background

Phospholipid scramblase 1 (PLSCR1) is a member of the PLSCR protein family. These proteins are ATP-independent lipid translocators localized to the plasma membrane and is involved in a calcium dependent, nonspecific and rapid redistribution (scrambling) of phospholipids when a perturbation of plasma membrane asymmetry is needed for the cell (e.g. following cell activation, injury, or apoptosis). The expression of PLSCR1 is found in a variety of tissue and can be stress-induced. Upon stimulation (e.g. interferon stimulation), a portion of newly synthesized PLSCR1 is imported into the nucleus (instead of inserted into the plasma membrane) and interacts with DNA, consistent with a role in gene regulation. PLSCR1 may be closely associated with the pathophysiology underlying infection and inflammation, which manifest marked changes in energy consumption and lipid metabolism.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PLSCR1
• Entrez:
  • 5359(Human)
• OMIM:
  • 604170(Human)
• Uniprot:
  • AAH32718(Human)