PHKA2 Antibody - BSA Free

Immunohistochemistry: PHKA2 Antibody - BSA Free [NBP3-47161] - Immunohistochemistry of paraffin-embedded human liver tissue slide using (PHKA2 Antibody) at dilution of 1:50

Western Blot: PHKA2 Antibody - BSA Free [NBP3-47161] - SMMC-7721 cells were subjected to SDS PAGE followed by western blot with (PHKA2 Antibody) at dilution of 1:600

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

PHKA2 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit PHKA2 Antibody - BSA Free (NBP3-47161) is a polyclonal antibody validated for use in IHC, WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: phosphorylase kinase, alpha 2(liver). (Uniprot# P46019)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PHKA2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry 1:20-1:200
  • Western Blot 1:500-1:2000
• Theoretical MW: 138 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS, 50% Glycerol, pH (7.3)
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for PHKA2 Antibody - BSA Free

• GSD9A
• MGC133071
• PHK
• PHKLA
• phosphorylase b kinase regulatory subunit alpha liver isoform
• phosphorylase b kinase regulatory subunit alpha, liver isoform
• Phosphorylase kinase alpha L subunit
• phosphorylase kinase alpha-subunit
• phosphorylase kinase, alpha 2 (liver)
• PYK
• PYKL
• XLG
• XLG2

Background

PHKA2, also known as Phosphorylase b kinase regulatory subunit alpha, liver isoform, is a 1,235 amino acid protein that is 138 kDa, predominantly expressed in liver and other non-muscle tissues, acts as a catalyzer of the phosphorylation of serine in certain substrates, including troponin I, and its alpha chain may bind calmodulin. This protein has been linked to several diseases and disorders including glycogen storage disease, x-linked liver glycogenosis type 1, hepatitis, glycogen storage disease, type ixa2, glycogen storage disease, type ixa1, coffin-lowry syndrome, muscle glycogenosis, Japanese encephalitis, retinoschisis, metabolic disorders, encephalitis, chagas disease, fanconi syndrome, hepatitis c hypertriglyceridemia, myopathy, hypercholesterolemia, hepatocellular carcinoma, psoriasis, and pneumonia. The PHKA2 protein has also shown an interaction with SMAD9, UBE3A, RAF1, LMLN, and METTL13 in the metabolism of carbohydrates, glycogen breakdown (glycogenolysis), metabolism, glucose metabolism, calcium signaling pathway, insulin signaling pathway, and signal transduction cAMP signaling pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PHKA2