PGLYRP4/PGRP-I beta Antibody (474034)

• Reactivity: Hu
• Applications: WB, IP
• Clone: 474034
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: LYOPH

PGLYRP4/PGRP-I beta Antibody (474034) Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human PGLYRP4/PGRP-I beta
  Asp18-His373
  Accession # Q96LB8
• Specificity: Detects human PGLYRP4/PGRP-I beta in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse PGRP-I beta or recombinant human PGRP-S is observed.
• Source: N/A
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: PGLYRP4
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 25 ug/mL
  • Western Blot 1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for PGLYRP4/PGRP-I beta Antibody (474034)

• peptidoglycan recognition protein 4
• peptidoglycan recognition protein I beta
• Pglyrp-1 beta
• PGLYRP4
• PGRPI beta
• PGRP-I beta
• PGRP-I-beta

Background

Peptidoglycan recognition protein intermediate beta (PGRP-I beta ), also known as peptidoglycan recognition protein 4 (PGLRP4), belongs to the family of human recognition molecules that bind peptidoglycan (a ubiquitous component of bacterial cell walls) and gram-positive bacteria as part of the innate immune response. It has N-acetylmuramoyl-L-alanine amidase activity and is primarily expressed in the esophagus, where it is thought to play a role in host antimicrobial defense. PGRP-I beta has two predicted transmembrane domains and extracellular N- and C-termini. The amino acid sequence of human PGRP- I beta is 99% and 76% identical to that of chimpanzee and mouse.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PGLYRP4
• Uniprot:
  • Q96LB8()