PGLYRP4/PGRP-I beta Products

Antibodies
PGLYRP4/PGRP-I beta Antibody ...
PGLYRP4/PGRP-I beta Antibody (474034)
MAB3018
Species: Hu
Applications: WB, IP
Host: Mouse Monoclonal
PGLYRP4/PGRP-I beta Antibody
PGLYRP4/PGRP-I beta Antibody
AF3018
Species: Hu
Applications: WB
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
RNAi
PGLYRP4/PGRP-I beta RNAi
PGLYRP4/PGRP-I beta RNAi
H00057115-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

The primary immune recognition is based on structures common among invading pathogens. Bacterial surface molecules, such as lipopolysaccharide (LPS) and peptidoglycan (PGN), are known to elicit immune reactions ranging from cytokine release to fever. Recently, a family of proteins called peptidoglycan recognition protein (PGRP) has been identified in mouse and human that binds to peptidoglycans expressed on Gram-positive bacteria. Peptidoglycan (PGN) is an essential cell wall component of virtually all bacteria (1,2) and, thus, it is an excellent target for recognition by the eukaryotic innate immune system. The PGRPs (PGRP-L, PGRP-S, PGRP-I alpha, and PGRP-I beta) define a new family of human pattern recognition molecules (3). PGRP-L is primarily expressed in the liver. Although liver is not considered a primary immune organ, liver participates in host defenses by producing acute phase proteins (by hepatocytes) in response to infections and by clearing microorganisms from blood (4-5).

Bioinformatics

Product By Gene ID 57115
Alternate Names
  • peptidoglycan recognition protein I beta
  • PGRP-I-beta
  • peptidoglycan recognition protein 4

Pathways for PGLYRP4/PGRP-I beta

View related products by pathway and learn more about each of the pathways below.

Immune Response
Inflammatory Response
Keratinocyte Proliferation
Innate Immune Response
Pathogenesis
Localization

PTMs for PGLYRP4/PGRP-I beta

Learn more about PTMs related to PGLYRP4/PGRP-I beta.

Cleavage

Bioinformatics Tool for PGLYRP4/PGRP-I beta

Discover related pathways, diseases and genes to PGLYRP4/PGRP-I beta. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.