PEX6 Antibody (S233-8) [DyLight 488]

Product Discontinued

PEX6 Antibody (S233-8) [DyLight 488] Summary

• Immunogen: Fusion protein amino acids 2-294 (N-terminus) of human PEX6. Rat: 82% identity (243/293 amino acids identical). Mouse: 82% identity (244/294 amino acids identical). <50% identity with other PEX proteins.
• Localization: Cytoplasm , Peroxisome , Peroxisome Membrane
• Specificity: Less then 50% identity with other PEX proteins.Detects approx 100kDa.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: PEX6
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Immunogen displays sequence identity for non-tested species: Rat.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Alternate Names for PEX6 Antibody (S233-8) [DyLight 488]

• PAF2
• PAF-2peroxisome assembly factor 2
• Peroxin-6
• peroxisomal biogenesis factor 6peroxin-6
• Peroxisomal-type ATPase 1
• peroxisome biogenesis factor 6
• PXAAA1peroxisomal AAA-type ATPase 1

Background

PEX6 encodes a member of the AAA (ATPases associated with diverse cellular activities) family of ATPases. This member is a predominantly cytoplasmic protein, which plays a direct role in peroxisomal protein import and is required for PTS1 (peroxisomal targeting signal 1, a C-terminal tripeptide of the sequence ser-lys-leu) receptor activity. Mutations in this gene cause peroxisome biogenesis disorders of complementation group 4 and complementation group 6. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PEX6