Peptide YY Antibody (1) - BSA Free Summary
| Description |
Novus Biologicals Mouse Peptide YY Antibody (1) - BSA Free (NBP1-05167) is a monoclonal antibody validated for use in IHC and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee. |
| Immunogen |
Synthetic human PYY |
| Specificity |
Binds human PYY. Cross-reactivity with NPY or PP in solution is <0.1%. |
| Isotype |
IgG1 Kappa |
| Clonality |
Monoclonal |
| Host |
Mouse |
| Gene |
PYY |
| Purity |
Protein A or G purified |
| Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
| Dilutions |
- ELISA 1:16000
- Immunohistochemistry 1:10-1:500
- Immunohistochemistry-Paraffin 1:10-1:500
- Sandwich ELISA Capture
- Sandwich ELISA
|
| Application Notes |
ELISA: NBP1-05167 binds free PYY in solution. NBP1-05167 reacts in ELISA with PYY coated directly onto the microtiter well. Biotinylated NBP1-05167 can be used as a detection antibody with NBP2-23584 as a capture antibody for measuring PYY(3-36) by sandwich ELISA.
IHC: NBP1-05167 can be used in IHC. Please consult www.proteinatlas.org |
Packaging, Storage & Formulations
| Storage |
Store at 4C in the dark. |
| Buffer |
10mM Phosphate (pH 7.4) and 0.5M NaCl |
| Preservative |
0.09% Sodium Azide |
| Concentration |
1.0 mg/ml |
| Purity |
Protein A or G purified |
Alternate Names for Peptide YY Antibody (1) - BSA Free
Background
Peptide tyrosine-tyrosine (PYY) amide is a 36 amino-acid. PYY is a member of the pancreatic polypeptide (PP) family of peptides (neuropeptide Y (NPY), PYY and PP). While NPY is localized in neurons (both in the central and peripheral nervous system) and PP in the pancreatic islets, PYY is found in both neurons and the gut. PYY is released in response to food intake from the same endocrine cells (L cells) in the intestinal mucosa as the glucagon-like peptides and inhibits gall bladder secretion, gut motility and pancreatic secretion. These effects are similar to those of PP and overlap with the gut inhibitory activity of GLP-1.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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