Pepsinogen I Antibody (HMV318)

IHC-P analysis of human stomach tissue using Pepsinogen I antibody (HMV318).Strong pepsinogen I positivity in chief cells of corpus glands.

IHC-P analysis of human gastric adenocarcinoma tissue of the fundic gland type (GA-FG) using Pepsinogen I antibody (HMV318).Gastric adenocarcinoma of the fundic gland type (GA-FG) with distinct pepsinogen I staining of tumor cells.

IHC-P analysis of human gastric antrum tissue using Pepsinogen I antibody (HMV318).Pepsinogen I positivity in few glands formed by chief cells in the corpus-antrum transition zone.

• Reactivity: Hu
• Applications: IHC
• Clone: HMV318
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated

Pepsinogen I Antibody (HMV318) Summary

• Description: Novus Biologicals Rabbit Pepsinogen I Antibody (HMV318) (NBP3-48802) is a recombinant monoclonal antibody validated for use in IHC. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: Recombinant fragmemt of human Pepsinogen I
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: PGA3
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:100-1:200
• Application Notes: IHC-P: Heat-induced antigen retrieval for 5 minutes in an autoclave at 121C in Antigen retrieval buffer, pH 7.8.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, 2% BSA
• Preservative: 0.025% Proclin 300
• Purity: Protein A purified

Alternate Names for Pepsinogen I Antibody (HMV318)

• pepsinogen 3, group I (pepsinogen A)

Background

Pepsinogen consists of a single polypeptide chain of 375 amino acids with an average molecular weight of 42 kDa. Pepsinogen I is synthesized by gastric chief cells and mucous neck cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PGA3