Pepsinogen I Antibody (8003 (99/12)) [Janelia Fluor® 549]

• Reactivity: Hu
• Applications: ELISA, Func, IHC
• Clone: 8003 (99/12)
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Janelia Fluor 549

Pepsinogen I Antibody (8003 (99/12)) [Janelia Fluor® 549] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: Purified human pepsinogen 1
• Localization: Secreted
• Specificity: NB100-62239 recognises human Pepsinogen I, a zymogen or proenzyme secreted by Chief cells in the stomach. It is cleaved to form pepsin both in an autocatalytic fashion and by pepsin itself. In humans there are two related forms of pepsin, Pepsinogen I (also known as pepsinogen A), and Pepsinogen II (also known as Pepsinogen B or progastricsin).
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: PGA3
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Radioimmunoassay
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NB100-62239. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Pepsinogen I Antibody (8003 (99/12)) [Janelia Fluor® 549]

• pepsinogen 3, group I (pepsinogen A)

Background

Pepsinogen consists of a single polypeptide chain of 375 amino acids with an average molecular weight of 42 kDa. Pepsinogen I is synthesized by gastric chief cells and mucous neck cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PGA3