PDE9A Antibody - BSA Free

Immunocytochemistry/Immunofluorescence: PDE9A Antibody [NBP1-86478] - Staining of human cell line U-2 OS shows localization to nucleoplasm & vesicles.

Analysis in human prostate and liver tissues using Anti-PDE9A antibody. Corresponding PDE9A RNA-seq data are presented for the same tissues.

Immunohistochemistry-Paraffin: PDE9A Antibody [NBP1-86478] - Staining of human prostate shows high expression.

Immunohistochemistry-Paraffin: PDE9A Antibody [NBP1-86478] - Staining of human liver shows low expression as expected.

• Reactivity: Hu, Mu, Rt
• Applications: ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

PDE9A Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit PDE9A Antibody - BSA Free (NBP1-86478) is a polyclonal antibody validated for use in IHC and ICC/IF. Anti-PDE9A Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: ECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMF
• Predicted Species: Mouse (95%), Rat (95%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PDE9A
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF,Fixation Permeabilization: Use PFA/Triton X-100.
• Control Peptide:

  PDE9A Protein (NBP1-86478PEP)

Reactivity Notes

Reactivity reported in scientific literature (PMID: 20371479)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for PDE9A Antibody - BSA Free

• CGMP-specific 3'-5'-cyclic phosphodiesterase type 9
• CGMP-specific 3'-5'-cyclic phosphodiesterase type 9, EC 3.1.4.1710phosphodiesterase PDE9A21
• EC 3.1.4.35
• FLJ90181
• high affinity cGMP-specific 3'-5'-cyclic phosphodiesterase 9A
• HSPDE9A2
• PDE9A
• phosphodiesterase 9A

Background

The protein encoded by the PDE9A gene catalyzes the hydrolysis of cAMP and cGMP to their corresponding monophosphates. The encoded protein plays a role in signal transduction by regulating the intracellular concentration of these cyclic nucleotides. Multiple transcript variants encoding several different isoforms have been found for this gene. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for PDE9A Antibody (NBP1-86478)(1)

Publication using NBP1-86478

• Saito Y, Kitamura H, Hijikata A et al. Identification of therapeutic targets for quiescent, chemotherapy-resistant human leukemia stem cells. Sci Transl Med 2010-02-03 [PMID: 20371479]

Bioinformatics

• Gene Symbol: PDE9A