PDE6G Antibody

Western Blot: PDE6G Antibody [NB120-5664] - Analysis of sheep retinal extracts.

Product Discontinued

PDE6G Antibody Summary

• Immunogen: Synthetic Peptide: M(1) N L E P P K A E I R S A T R(15) C
• Specificity: NB120-5664 detects phosphodiesterase 6 gamma (PDE6 gamma) from sheep retinal extract and bovine rod outer segment membranes as well as purified bovine PDE6 gamma.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PDE6G
• Purity: Ammonium sulfate precipitation

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500
• Application Notes: WB: Detects an approx. 10 kDa protine representing PDE6 gamma from sheep retinal extract.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Ammonium sulfate precipitation

Alternate Names for PDE6G Antibody

• DKFZp686C0587
• GMP-PDE gamma
• MGC125749
• PDE6G
• PDEG
• phosphodiesterase 6G, cGMP-specific, rod, gamma
• retinal rod rhodopsin-sensitive cGMP 3'-5'-cyclic phosphodiesterase subunit gamma
• rod cG-PDE G
• RP57

Background

This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PDE6G