PCK2 Antibody

Western Blot: PCK2 Antibody [H00005106-D01P] - Analysis of PCK2 expression in human liver.

Western Blot: PCK2 Antibody [H00005106-D01P] - Analysis of PCK2 expression in HepG2.

Western Blot: PCK2 Antibody [H00005106-D01P] - Analysis of PCK2 expression in transfected 293T cell line by PCK2 polyclonal antibody.Lane 1: PCK2 transfected lysate(70.70 KDa).Lane 2: Non-transfected lysate.

Product Discontinued

PCK2 Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: PCK2 (AAH01454.1, 1 a.a. - 640 a.a.) full-length human protein. MAALYRPGLRLNWHGLSPLGWPSCRSIQTLRVLSGDLGQLPTGIRDFVEHSARLCQPEGIHICDGTEAENTATLTLLEQQGLIRKLPKYNNCWLARTDPKDVARVESKTVIVTPSQRDTVPLPPGGARGQLGNWMSPADFQRAVDERFPGCMQGRTMYVLPFSMGPVGSPLSRIGVQLTDSAYVVASMRIMTRLGTPVLQALGDGDFVKCLHSVGQPLTGQGEPVSQWPCNPEKTLIGHVPDQREIISFGSGYGGNSLLGKKCFALRIASRLARDEGWLAEHMLILGITSPAGKKRYVAAAFPSACGKTNLAMMRPALPGWKVECVGDDIAWMRFDSEGRLRAINPENGFFGVAPGTSATTNPNAMATIQSNTIFTNVAETSDGGVYWEGIDQPLPPGVTVTSWLGKPWKPGDKEPCAHPNSRFCAPARQCPIMDPAWEAPEGVPIDAIIFGGRRPKGVPLVYEAFNWRHGVFVGSAMRSESTAAAEHKGKIIMHDPFAMRPFFGYNFGHYLEHWLSMEGRKGAQLPRIFHVNWFRRDEAGHFLWPGFGENARVLDWICRRLEGEDSARETPIGLVPKEGALDLSGLRAIDTTQLFSLPKDFWEQEVRDIRSYLTEQVNQDLPKEVLAELEALERRVHKM
• Specificity: Reacts with phosphoenolpyruvate carboxykinase 2 (mitochondrial).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PCK2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: This antibody is reactive against tissue and transfected lysate in WB and as a detection antibody in ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for PCK2 Antibody

• EC 4.1.1.32
• PE
• PEPCK
• PEPCK2PEP carboxykinase
• PEPCK-M
• phosphoenolpyruvate carboxykinase [GTP], mitochondrial
• phosphoenolpyruvate carboxykinase 2 (mitochondrial)
• Phosphoenolpyruvate carboxylase
• phosphopyruvate carboxylase

Background

This gene encodes a member of the phosphoenolpyruvate carboxykinase (GTP) family. The protein is a mitochondrial enzyme that catalyzes the conversion of oxaloacetate to phosphoenolpyruvate in the presence of GTP. A cytosolic form encoded by a different gene has also been characterized and is the key enzyme of gluconeogenesis in the liver. The encoded protein may serve a similar function, although it is constitutively expressed and not modulated by hormones such as glucagon and insulin that regulate the cytosolic form. Alternatively spliced transcript variants have been described. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PCK2
• Entrez:
  • 5106(Human)
• Uniprot:
  • AAH01454.1(Human)