PCK2 Products

Description

PCK2 encodes a member of the phosphoenolpyruvate carboxykinase (GTP) family. The protein is a mitochondrial enzyme that catalyzes the conversion of oxaloacetate to phosphoenolpyruvate in the presence of GTP. A cytosolic form encoded by a different gene has also been characterized and is the key enzyme of gluconeogenesis in the liver. The encoded protein may serve a similar function, although it is constitutively expressed and not modulated by hormones such as glucagon and insulin that regulate the cytosolic form. Alternatively spliced transcript variants have been described.

Bioinformatics

Uniprot	AAH01454 Human AAH01454.1 Human NM_004563 Human NP_004554.2 Human Q16822 (Precursor) Human Q16822 Human
Product By Gene ID	5106
Alternate Names	EC 4.1.1.32 PE PEPCK PEPCK2PEP carboxykinase PEPCK-M phosphoenolpyruvate carboxykinase [GTP], mitochondrial phosphoenolpyruvate carboxykinase 2 (mitochondrial) Phosphoenolpyruvate carboxylase phosphopyruvate carboxylase

Research Areas for PCK2

Find related products by research area and learn more about each of the different research areas below.

Lipid and Metabolism