PCAF Antibody [DyLight 755]

Product Discontinued

PCAF Antibody [DyLight 755] Summary

• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-86 of human PCAF (NP_003875.3).
  
  Sequence:
  MSEAGGAGPGGCGAGAGAGAGPGALPPQPAALPPAPPQGSPCAAAAGGSGACGPATAVAAAGTAEGPGGGGSARIAVKKAQLRSAP
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KAT2B
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for PCAF Antibody [DyLight 755]

• CREBBP-associated factor
• EC 2.3.1.48
• GCN5
• GCN5L
• Histone acetylase PCAF
• histone acetyltransferase KAT2B
• Histone acetyltransferase PCAF
• K(lysine) acetyltransferase 2B
• KAT2B
• Lysine acetyltransferase 2B
• P
• P/CAFGCN5
• P300/CBP-associated factorCAF
• PCAF

Background

CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KAT2B