PAWR / PAR4 Antibody (3G9H7,4H12E9)

Images

 
Immunohistochemistry-Paraffin: PAWR / PAR4 Antibody (3G9H7,4H12E9) [NBP1-52416] - Analysis of anti-PAWR / PAR4 antibody with human brain, cortex at dilution 1:200.
Immunohistochemistry-Paraffin: PAWR / PAR4 Antibody (3G9H7,4H12E9) [NBP1-52416] - Analysis of anti-PAWR / PAR4 antibody with human small intestine at dilution 1:200.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, IHC-P
Clone
3G9H7,4H12E9
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

PAWR / PAR4 Antibody (3G9H7,4H12E9) Summary

Immunogen
Purified recombinant fragment of PAR4(aa1-330) expressed in E. coli.
Specificity
Human PAWR
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
PAWR
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:2000
  • ELISA 1:10000
  • Immunohistochemistry-Paraffin 1:200

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Ascites
Preservative
0.03% Sodium Azide
Purity
Unpurified

Alternate Names for PAWR / PAR4 Antibody (3G9H7,4H12E9)

  • Par-4
  • PAR4prostate apoptosis response protein 4
  • PRKC apoptosis WT1 regulator protein
  • PRKC, apoptosis, WT1, regulator
  • Prostate apoptosis response 4 protein
  • prostate apoptosis response protein PAR-4
  • transcriptional repressor PAR4
  • WT1-interacting protein

Background

Prostate apoptosis response 4 (Par4) is a 38kD protein originally identified as the product of a gene that is upregulated in prostate tumor cells undergoing apoptosis. It is a leucine zipper and death domain containing protein whose levels increase in neurons undergoing apoptosis as a result of trophic factor withdrawal or exposure to oxidative and metabolic insults. Par4 levels are reported to be increased in their lumbar spinal cord specimens further suggesting a role in neuronal degeneration. The tumor suppressor WT1 represses and activates transcription. The loss and/or imbalance of the dual transcriptional activity of WT1 may contribute to Wilms tumor. Par4 is a WT1 interacting protein that also functions as a transcriptional repressor.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol PAWR
Entrez
Uniprot