PATZ Antibody

Images

 
Western Blot: PATZ Antibody [H00023598-B01P] - Analysis of PATZ1 expression in transfected 293T cell line by PATZ1 polyclonal antibody. Lane 1: ZNF278 transfected lysate(59.07 KDa). Lane 2: Non-transfected lysate.
Immunocytochemistry/ Immunofluorescence: PATZ Antibody [H00023598-B01P] - Analysis of purified antibody to ZNF278 on HeLa cell. (antibody concentration 10 ug/ml)

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, ICC/IF
Clonality
Polyclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

PATZ Antibody Summary

Immunogen
ZNF278 (NP_114440.1, 1 a.a. ~ 537 a.a) full-length human protein.MERVNDASCGPSGCYTYQVSRHSTEMLHNLNQQRKNGGRFCDVLLRVGDESFPAHRAVLAACSEYFESVFSAQLGDGGAADGGPADVGGATAAPGGGAGGSRELEMHTISSKVFGDILDFAYTSRIVVRLESFPELMTAAKFLLMRSVIEICQEVIKQSNVQILVPPARADIMLFRPPGTSDLGFPLDMTNGAALAANSNGIAGSMQPEEEAARAAGAAIAGQASLPVLPGVDRLPMVAGPLSPQLLTSPFPSVA
Specificity
ZNF278,
Isotype
IgG
Clonality
Polyclonal
Host
Mouse
Gene
PATZ1
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • ELISA
  • Immunocytochemistry/Immunofluorescence
Application Notes
This antibody is useful for ELISA, immunofluorescence, and Western Blot.

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for PATZ Antibody

  • dJ400N23
  • MAZRPOZ-, AT hook-, and zinc finger-containing protein 1
  • PATZZinc finger and BTB domain-containing protein 19
  • POZ (BTB) and AT hook containing zinc finger 1
  • Protein kinase A RI subunit alpha-associated protein
  • RIAZBTB/POZ domain zinc finger transcription factor
  • ZBTB19BTB-POZ domain zinc finger transcription factor
  • Zinc finger protein 278Zinc finger sarcoma gene protein
  • ZNF278POZ-AT hook-zinc finger protein
  • ZSGMAZ-related factor

Background

The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1;22)(p36.1;q12). The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PATZ1
Entrez
Uniprot