Patched 2/PTCH2 Antibody (865619) [DyLight 594]

• Reactivity: Mu
• Applications: IHC
• Clone: 865619
• Clonality: Monoclonal
• Host: Rat
• Conjugate: DyLight 594

Patched 2/PTCH2 Antibody (865619) [DyLight 594] Summary

• Immunogen: E. coli-derived recombinant mouse Patched 2/PTCH2
  Glu79-Ser394
  Accession # O35595
• Specificity: Detects mouse Patched 2/PTCH2 in ELISAs. In direct ELISAs, less than 10% cross-reactivity with recombinant mouse Patched 1 or recombinant human Patched 2 is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Gene: PTCH2
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Patched 2/PTCH2 Antibody (865619) [DyLight 594]

• patched (Drosophila) homolog 2
• Patched 2
• patched homolog 2 (Drosophila)
• patched homolog 2
• protein patched homolog 2
• ptc2
• PTCH2

Background

Mutations of the human Patched tumor suppressor gene (PTCH) have been identified in individuals with the nevoid basal cell carcinoma syndrome (NBCCS) as well as in sporadic basal cell carcinomas and medulloblastomas. PTCH2 has a frameshift mutation resulting in a truncated PTCH2 protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PTCH2