Patched 1/PTCH Antibody


Western Blot: Patched 1/PTCH Antibody [NB100-41101] - Analysis of Patched 1 in Human Brain lysate using NB100-41101 (1ug/ml).
Western Blot: Patched 1/PTCH Antibody [NB100-41101] - (1ug/ml) staining of Human Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Product Details

Reactivity Hu, MuSpecies Glossary
Applications WB, ICC/IF, PEP-ELISA
0.5 mg/ml

Order Details

Patched 1/PTCH Antibody Summary

Peptide with sequence C-HPESRHHPPSNPRQQ corresponding to internal region according to NP_000255.2, NP_001077072.1, NP_001077071.1, NP_001077075.1.
This antibody is expected to recognise all four reported isoforms (NP_000255.2; NP_001077072.1; NP_001077071.1; NP_001077075.1). Reported variants represent identical protein (NP_001077075.1; NP_001077076.1; NP_001077073.1; NP_001077074.1).
Immunogen affinity purified
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Packaging, Storage & Formulations

Store at -20C. Avoid freeze-thaw cycles.
Tris saline, pH 7.3 with 0.5% BSA.
0.02% Sodium Azide
0.5 mg/ml
Immunogen affinity purified


Application Notes
ICC/IF successful usage for C3H10T1/2 cells and mouse embryonic primary cells. WB: Approx. 150 kDa band observed in human brain lysates (calculated MW of 161 kDa band according to NP_000255.1).
Read Publication using NB100-41101.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Canine, Porcine, Bovine. Mouse reactivity reported in scientific literature (PMID: 21533246).

Alternate Names for Patched 1/PTCH Antibody

  • BCNS
  • BCNSFLJ42602
  • FLJ26746
  • HPE7
  • mes
  • patched (Drosophila) homolog
  • patched 1
  • patched homolog (Drosophila)
  • patched homolog 1 (Drosophila)
  • patched homolog 1
  • protein patched homolog 1
  • PTC
  • ptc1
  • PTCH protein +12b
  • PTCH protein +4'
  • PTCH protein -10
  • PTCH
  • PTCH1
  • PTCH11


This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis. This gene functions as a tumor suppressor. Mutations of this gene have been associated with nevoid basal cell carcinoma syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Patched 1/PTCH Antibody (NB100-41101)(1)

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Patched 1/PTCH Antibody (NB100-41101). (Showing 1 - 1 of 1 FAQ).

  1. I need a proven anti-human Ptch1 antibody that maps C-terminus of Ptch1 protein which is thus appropriate for all isoforms of human Ptch1 protein. Can you please suggest any which can be used for Western blotting?
    • NB100-41101 is expected to recognize all isoforms. NBP2-19705, NBP1-71662, 21130002, and NBP1-59455 should all suit your needs as well. Further details about each product can be found on their individual datasheets.

Positive Control Lysate(s)

Secondary Antibodies


Isotype Controls

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Contact Information

Product PDFs


Gene Symbol PTCH1

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