Pappalysin-2/PAPP-A2 Antibody - BSA Free

Immunohistochemistry-Paraffin: Pappalysin-2/PAPP-A2 Antibody [NBP1-87340] - Analysis in human placenta and prostate tissues using NBP1-87340 antibody. Corresponding PAPPA2 RNA-seq data are presented for the same tissues.

Immunohistochemistry-Paraffin: Pappalysin-2/PAPP-A2 Antibody [NBP1-87340] - Staining of human cerebral cortex, liver, placenta and prostate using Anti-PAPPA2 antibody NBP1-87340 (A) shows similar protein distribution across tissues to independent antibody NBP1-87339 (B).

Immunohistochemistry-Paraffin: Pappalysin-2/PAPP-A2 Antibody [NBP1-87340] - Staining of human cerebral cortex shows no positivity in neurons as expected.

Immunohistochemistry-Paraffin: Pappalysin-2/PAPP-A2 Antibody [NBP1-87340] - Staining of human prostate shows low expression as expected.

Immunohistochemistry-Paraffin: Pappalysin-2/PAPP-A2 Antibody [NBP1-87340] - Staining of human placenta shows moderate cytoplasmic positivity in trophoblastic cells.

Immunohistochemistry-Paraffin: Pappalysin-2/PAPP-A2 Antibody [NBP1-87340] - Staining of human liver shows no positivity in hepatocytes as expected.

• Reactivity: Hu
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Pappalysin-2/PAPP-A2 Antibody - BSA Free Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: NPAGLRGAVEEPAAPWVGDSPIGQSELLGDDDAYLGNQRSKESLGEAGIQKGSAMAATTTTAIFTTLNEPKPETQRRGWAKSRQRRQVWKRRAEDGQGDSGISSHFQPWPKH
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PAPPA2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  Pappalysin-2/PAPP-A2 Protein (NBP1-87340PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for Pappalysin-2/PAPP-A2 Antibody - BSA Free

• EC 3.4.24.-
• PAPPA2
• PAPP-A2
• PAPP-A2pappalysin-2
• pappalysin 2
• Pappalysin2
• Pappalysin-2
• PAPPE
• PAPP-E
• PLAC3
• placenta-specific 3
• pregnancy-associated plasma preproprotein-A2
• Pregnancy-associated plasma protein A2
• Pregnancy-associated plasma protein E1

Background

Metalloproteinase which specifically cleaves IGFBP-5. Shows limited proteolysis toward IGFBP-3

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PAPPA2