Pancreatic Amylase Alpha Antibody (6A9/1)

Product Discontinued

Pancreatic Amylase Alpha Antibody (6A9/1) Summary

• Immunogen: Native pancreatic amylase
• Localization: Secreted protein; extracellular space.
• Specificity: This antibody recognises human pancreatic amylase, a secreted enzyme that catalyses the endohydrolysis of (1->4)-alpha-D-glucosidic linkages in oligosaccharides and polysaccharides. This antibody showns minimal cross-reactivity with salivary amylase.
• Isotype: IgM
• Clonality: Monoclonal
• Host: Mouse
• Gene: AMY2A
• Purity: Ammonium sulfate precipitation

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Ammonium sulfate precipitation

Alternate Names for Pancreatic Amylase Alpha Antibody (6A9/1)

• AMY2
• AMY2A amylase, alpha 2A (pancreatic)
• AMY2B
• PA
• pancreatic alpha-amylase

Background

Pancreatic amylase is a digestive enzyme secreted by the pancreas. It consists of a single polypeptide chain with a molecular weight of 54 kDa. Pancreatic amylase occurs in serum at a concentration of about 60ug/L, from a total amylase concentration in serum of about 120ug/L. Pancreatic amylase and salivary amylase are the products of separate genes and, although they share 98% amino acid sequence homology, they differ in molecular size, isoelectric point and antigenic properties. Measurement of amylase concentrations in serum is a diagnostic test for various pancreatic disorders (especially acute and relapsing pancreatitis).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: AMY2A
• Entrez:
  • 279(Human)
• Uniprot:
  • P04746(Human)