PALB2 Antibody

Images

 
Western Blot: PALB2 Antibody [21340002] - HEK293T cells plated at million cell in 10 cm plate overnight before treating with 0.5ug/mL of MMC for 24 hr. Cells were lysed using standard RIPA buffer and 30ug of the samples ...read more
ELISA: PALB2 Antibody [21340002] - The affinity purified antibody was serially diluted onto anELISA plate coated with a recombinant protein fragment.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

PALB2 Antibody Summary

Immunogen
This antibody is specific for the N Terminus Region of the target protein (NM_024675).
Specificity
This product is specific for Human PALB2.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PALB2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000
  • ELISA 1:100-1:2000
Application Notes
This antibody is useful in ELISA.
Theoretical MW
131.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Reviewed Applications
Read 1 Review rated 5
using
21340002 in the following applications:

Publications
Read Publications using
21340002 in the following applications:

  • 2 publications

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
Preservative
No Preservative
Purity
Immunogen affinity purified

Notes

Manufactured by SDIX's proprietary Genomic Antibody Technology™. GAT FAQs.

Alternate Names for PALB2 Antibody

  • DKFZp667I166
  • DKFZp686E1054
  • FANCNFLJ21816
  • partner and localizer of BRCA2
  • PNCA3

Background

PALB2 (partner and localizer of BRCA2) interacts with BRCA2 and promotes BRCA2 localization and stability. PALB2 is also known as FANCN. Bi-allelic mutations in PALB2 result in Fanconi anemia disorder and breast cancer susceptibility. At the cellular level, PALB2 is important to the DNA damage response and chromosome stability and is essential to BRCA2 function.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for PALB2 Antibody (21340002)(3)

Review for PALB2 Antibody (21340002) (1) 51

Average Rating: 5
(Based on 1 review)
We have 1 review tested in 1 species: Human.

Reviews using 21340002:
Filter by Applications
WB
(1)
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Human
(1)
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Images Ratings Applications Species Date Details
Western Blot PALB2 21340002
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reviewed by:
Anonymous
WB Human 07/04/2017
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Summary

ApplicationWestern Blot
Sample TestedHek 293T cell lysate
SpeciesHuman

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FAQs for PALB2 Antibody (21340002) (0)

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Secondary Antibodies

 

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Diseases for PALB2 Antibody (21340002)

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Blogs on PALB2.

The recent relationship of BRCA1 and 53BP1
The p53-binding protein 1 (53BP1) is a DNA damage response factor, which is recruited to nuclear structures at the site of DNA damage.  DNA double-strand breaks (DSBs) are mutations that are detrimental to cell viability and genome stability, and m...  Read full blog post.

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Recent Reviews

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1
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1
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Anonymous
07/04/2017
Application: WB
Species: Human

Bioinformatics

Gene Symbol PALB2
Entrez
Uniprot