PAK4 Antibody

Images

 
Western Blot: PAK4 Antibody [NBP1-45763] - Analysis of PAK4 expression with COS cell lysate.

Product Details

Summary
Reactivity Hu, Mu, Rt, HaSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

PAK4 Antibody Summary

Immunogen
Synthetic peptide corresponding to the N-terminus of human Pak4 (BAF84528).
Specificity
The antibody recognizes ~60-70 kDa Pak4 in samples of human, mouse, and rat origins.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PAK4
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.5 - 4 ug/mL
Control
PAK4 Knockout 293T Cell Lysate

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2), 5 mM EDTA, 0.5% BSA, 30% Glycerol
Preservative
0.03% Proclin
Concentration
0.5 mg/ml
Purity
Affinity purified

Alternate Names for PAK4 Antibody

  • EC 2.7.11
  • EC 2.7.11.1
  • KIAA1142
  • p21 protein (Cdc42/Rac)-activated kinase 4
  • p21(CDKN1A)-activated kinase 4
  • p21-activated kinase 4
  • PAK4
  • PAK-4
  • protein kinase related to S. cerevisiae STE20, effector for Cdc42Hs
  • serine/threonine-protein kinase PAK 4

Background

p21-activated kinase 4 (PAK4) is a member of a family of serine/threonine protein kinase defined by their interaction with the small GTPases, Cdc42 and Rac (1-2). The PAK proteins can be essentially divided into two categories, groups I (PAK1, PAK2 and PAK3) and group II (PAK4, PAK5 and PAK6), based on their structures (3). PAK4 has been shown to regulate cytoskeletal organization and to protect cells from apoptosis induced by multiple stimuli, including serum withdrawal, tumor necrosis factor- (TNF) treatment, or UV irradiation (4). PAK4 expression is elevated in many cancer cell lines, and activated PAK4 is highly transforming, suggesting an important role in tumorigenesis (5).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP2-67895
Species: Hu, Mu, Rt
Applications: WB, Flow, IHC, IHC-P, IP
AF4265
Species: Hu, Mu, Rt
Applications: WB
NB100-56159
Species: Hu, Mu, Rt, Ca
Applications: WB, IHC, IHC-P, IP
AF887
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC, CyTOF-ready, ICFlow
NBP1-85802
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
MAB4696
Species: Hu, Rt
Applications: WB, IHC
NB100-82021
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NBP2-37573
Species: Hu, Mu, Rt, Pm
Applications: WB, ELISA, Flow, IHC, IHC-P
NBP2-67360
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP
NBP2-75607
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IHC-P
NBP2-22203
Species: Hu, Mu, Rt, Mk
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P
NB200-106
Species: Mu
Applications: WB, ELISA, ICC/IF, IHC, IHC-Fr, IHC-P
NBP2-25160
Species: Hu, Mu, Rt, Po, Bv, Ca, Eq
Applications: WB, ICC/IF, IHC
NBP1-58359
Species: Hu, Mu, Rt, Bv, Ca, Eq, GP
Applications: WB, IHC, IHC-P
NBP2-21577
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P, IP, KD
AF1280
Species: Mu
Applications: WB, Simple Western, IHC
NBP2-67484
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP
NBP1-45763
Species: Hu, Mu, Rt, Ha
Applications: WB
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Publications for PAK4 Antibody (NBP1-45763) (0)

There are no publications for PAK4 Antibody (NBP1-45763).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for PAK4 Antibody (NBP1-45763) (0)

There are no reviews for PAK4 Antibody (NBP1-45763). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for PAK4 Antibody (NBP1-45763) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Additional PAK4 Products

Bioinformatics Tool for PAK4 Antibody (NBP1-45763)

Discover related pathways, diseases and genes to PAK4 Antibody (NBP1-45763). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for PAK4 Antibody (NBP1-45763)

Discover more about diseases related to PAK4 Antibody (NBP1-45763).
 

Pathways for PAK4 Antibody (NBP1-45763)

View related products by pathway.

PTMs for PAK4 Antibody (NBP1-45763)

Learn more about PTMs related to PAK4 Antibody (NBP1-45763).
 

Research Areas for PAK4 Antibody (NBP1-45763)

Find related products by research area.

Blogs on PAK4

There are no specific blogs for PAK4, but you can read our latest blog posts.
Recombinant Monoclonal Antibodies

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our PAK4 Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol PAK4
Entrez
Uniprot