PAK3 Antibody

Images

 
Western Blot: PAK3 Antibody [NBP2-19682] - Sample (30 ug of whole cell lysate) A: NIH-3T3 B: BCL-1 7. 5% SDS PAGE gel, diluted at 1:1000.
Western Blot: PAK3 Antibody [NBP2-19682] - Sample (30 ug of whole cell lysate) A: IMR32 7. 5% SDS PAGE gel, diluted at 1:1000.

Product Details

Summary
Reactivity Hu, Mu, Rt, Bv, Mk, XpSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.74 mg/ml

Order Details

PAK3 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human PAK3. The exact sequence is proprietary.
Predicted Species
Rat (100%), Xenopus (100%), Bovine (100%), Monkey (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PAK3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
Theoretical MW
61 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Expected cross reactivity based on sequence homology: Xenopus laevis (100%), Chimpanzee (100%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.0), 1.0% BSA and 20% Glycerol
Preservative
0.01% Thimerosal
Concentration
0.74 mg/ml
Purity
Immunogen affinity purified

Alternate Names for PAK3 Antibody

  • beta-PAK
  • bPAK
  • CDKN1A
  • EC 2.7.11
  • EC 2.7.11.1
  • hPAK3
  • mental retardation, X-linked 47
  • MRX30
  • MRX47
  • oligophrenin-3
  • OPHN3
  • p21 (CDKN1A)-activated kinase 3
  • p21 protein (Cdc42/Rac)-activated kinase 3
  • p21-activated kinase 3
  • PAK3
  • PAK-3
  • PAK3beta
  • serine/threonine-protein kinase PAK 3

Background

PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. The protein encoded by this gene forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1 proteins which then catalyzes a variety of targets. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of non-syndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol PAK3
Entrez