PAK3 Products

Antibodies
PAK3 Antibody
PAK3 Antibody
AF6897
Species: Hu, Mu
Applications: WB, IHC
Host: Sheep Polyclonal
Formulation Catalog # Availability Price  
PAK3 Antibody (1H7)
PAK3 Antibody (1H7)
H00005063-M07
Species: Hu, Mu, Pm
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
PAK3 Antibody (4G8F11) - BSA ...
PAK3 Antibody (4G8F11) - BSA Free
NBP2-61766
Species: Hu, Pm
Applications: WB, ELISA
Host: Mouse Monoclonal
Formulation Catalog # Availability Price  
Proteins
Recombinant Human PAK3 GST (N ...
Recombinant Human PAK3 GST (N-Term...
H00005063-Q01
Species: Hu
Applications: WB, ELISA, MA, AP
PAK3 Recombinant Protein Anti ...
PAK3 Recombinant Protein Antigen
NBP2-38890PEP
Species: Hu
Applications: AC

Description

p21-activated kinase 3 (PAK3) is a member of a family of serine/threonine protein kinase defined by their interaction with the small GTPases, Cdc42 and Rac (1-2). The PAK proteins can be essentially divided into two categories, group I (PAK1, PAK2 and PAK3) and group II (PAK4, PAK5 and PAK6), based on their structures (3). All six PAKs play an important role in diverse cellular processes, including cytoskeletal dynamics, growth/apoptotic signal transduction through MAP kinases, and regulation of transcription factors (4). PAK3 as well as PAK1 are mostly expressed in the nervous system and particularly in the hippocampus, in which they show a diffuse distribution throughout the soma and proximal dendrites (5). Mutations in PAK3 have been linked to nonsyndromic X-linked mental retardation (6).

Bioinformatics

Uniprot Human
Human
Human
Alternate Names
  • Beta-PAK
  • beta-PAK
  • bPAK
  • CDKN1A
  • EC 2.7.11
  • EC 2.7.11.1
  • hPAK3
  • mental retardation, X-linked 47
  • MRX30
  • MRX47
  • Oligophrenin-3
  • oligophrenin-3
  • OPHN3
  • p21 (CDKN1A)-activated kinase 3
  • p21 protein (Cdc42/Rac)-activated kinase 3
  • p21-activated kinase 3
  • PAK-3
  • PAK3beta
  • serine/threonine-protein kinase PAK 3

Research Areas for PAK3

Find related products by research area and learn more about each of the different research areas below.

Protein Kinase