p114RhoGEF Antibody - BSA Free

Immunohistochemistry: p114RhoGEF Antibody - BSA Free [NBP3-47967] - Immunohistochemistry of paraffin-embedded human pancreas cancer using (p114RhoGEF antibody) at dilution of 1:50

Western Blot: p114RhoGEF Antibody - BSA Free [NBP3-47967] - Mouse testis tissue were subjected to SDS PAGE followed by western blot with (p114RhoGEF antibody) at dilution of 1:300

• Reactivity: Hu, Mu
• Applications: WB, ELISA, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

p114RhoGEF Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit p114RhoGEF Antibody - BSA Free (NBP3-47967) is a polyclonal antibody validated for use in IHC, WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: rho/rac guanine nucleotide exchange factor(GEF) 18. (Uniprot# Q6ZSZ5)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ARHGEF18
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry 1:20-1:200
  • Western Blot 1:500-1:2000
• Application Notes: Theoretical Molecular Weight is 120-130 kDa

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS, 50% Glycerol, pH (7.3)
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for p114RhoGEF Antibody - BSA Free

• 114 kDa Rho-specific guanine nucleotide exchange factor
• EC 3.4.24
• EC 3.6.1
• KIAA0521rho guanine nucleotide exchange factor 18
• MGC15913
• p114RhoGEF
• P114-RhoGEF
• P114-RHO-GEF
• Rho/Rac guanine nucleotide exchange factor (GEF) 18
• Rho/Rac guanine nucleotide exchange factor 18
• Rho-specific guanine nucleotide exchange factor p114
• SA-RhoGEF
• Septin-associated RhoGEF

Background

Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ARHGEF18