p114RhoGEF Products

Description

Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. (provided by RefSeq)

Bioinformatics

Uniprot	AAH08016.1 Human NP_056133 Human Q6ZSZ5 Human
Product By Gene ID	23370
Alternate Names	114 kDa Rho-specific guanine nucleotide exchange factor EC 3.4.24 EC 3.6.1 KIAA0521rho guanine nucleotide exchange factor 18 MGC15913 p114RhoGEF P114-RhoGEF p114-Rho-GEF P114-RHO-GEF Rho/Rac guanine nucleotide exchange factor (GEF) 18 Rho/Rac guanine nucleotide exchange factor 18 Rho-specific guanine nucleotide exchange factor p114 SA-RhoGEF Septin-associated RhoGEF

Research Areas for p114RhoGEF

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Signal Transduction