OTUD5 Antibody Blocking Peptide

• Reactivity: Hu
• Applications: AC
• Concentration: 0.2 mg/ml

OTUD5 Antibody Blocking Peptide Summary

• Description: A blocking peptide containing 13 amino acids near the carboxy terminus of human OTUD5.

  Source: Synthetic

  (Accession #: EAW50723)

• Source: Synthetic
• Protein/Peptide Type: Antibody Blocking Peptide
• Gene: OTUD5
• Purity: N/A

Applications/Dilutions

• Dilutions:
  • Antibody Competition
• Application Notes: This peptide is useful as a blocking peptide for NBP1-76943.
  
  For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
• Preservative: 0.02% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: N/A

Alternate Names for OTUD5 Antibody Blocking Peptide

• Deubiquitinating enzyme A
• DKFZp761A052
• DUBAdeubiquinating enzyme A
• EC 3.4.19.12
• MGC104871
• OTU domain containing 5
• OTU domain-containing protein 5

Background

OTUD5 encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: OTUD5