We're moving to rndsystems.com. Come with us!

After August 17, 2026, Novus Biologicals products and services will no longer be available on this website; you will access all products and services on rndsystems.com. Create your R&D Systems online account today.

OTUD5 Products

Antibodies
OTUD5 Antibody
OTUD5 Antibody
NBP2-24634
Species: Hu, Mu, Rt, Pm, Ch, Pm, Ma-Op, RM
Applications: WB, IHC
Host: Rabbit Polyclonal
OTUD5 Antibody - BSA Free
OTUD5 Antibody - BSA Free
NBP1-85044
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Formulation Catalog # Availability Price  
Proteins
Recombinant Human OTUD5 GST ( ...
Recombinant Human OTUD5 GST (N-Ter...
H00055593-P01
Species: Hu
Applications: WB, ELISA, MA, AP
OTUD5 Recombinant Protein Ant ...
OTUD5 Recombinant Protein Antigen
NBP1-85044PEP
Species: Hu
Applications: AC
OTUD5 Antibody Blocking Pepti ...
OTUD5 Antibody Blocking Peptide
NBP1-76943PEP
Species: Hu
Applications: AC

Description

This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]

Bioinformatics

Product By Gene ID 55593
Alternate Names
  • Deubiquitinating enzyme A
  • DKFZp761A052
  • DUBAdeubiquinating enzyme A
  • EC 3.4.19.12
  • MGC104871
  • OTU domain containing 5
  • OTU domain-containing protein 5

Research Areas for OTUD5

Find related products by research area and learn more about each of the different research areas below.

Innate Immunity