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Osteocalcin Antibody (6F9G4E10) [DyLight 594]

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Summary
Product Discontinued
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    • Catalog Number
      NB100-62804DL594
    • Availability
      Product Discontinued

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Osteocalcin Antibody (6F9G4E10) [DyLight 594] Summary

Immunogen
Recombinant human osteocalcin protein
Specificity
This product recognizes intact human osteocalcin in a "2 site" assay and reacts with osteocalcin fragments corresponding to amino acids 1-19, 7-19 and 15-31 of the native molecule. It does not recognize fragments representing amino acids 20-42 or intact bovine osteocalcin.

Osteocalcin (Bone Gla Protein) is a 49 amino acid single chain vitamin K dependent protein (MW 5.8 kDa), made by osteoblasts that is a major component of the non-collagenous bone matrix. Serum osteocalcin is elevated in diseases characterized by increased bone turnover such as osteoporosis, hyperparathyroidism and Paget's disease, and low in conditions associated with low bone turnover such as hypoparathyroidism and growth hormone deficiency.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
BGLAP
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • ELISA
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Does not react with: Bovine, Mouse, Rat.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Osteocalcin Antibody (6F9G4E10) [DyLight 594]

  • BGLAP
  • BGP
  • bone gamma-carboxyglutamate (gla) protein (osteocalcin)
  • bone gamma-carboxyglutamate (gla) protein
  • Bone Gla protein
  • Gamma-carboxyglutamic acid-containing protein
  • OC
  • OCN
  • Osteocalcin

Background

Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NB100-62804DL594
Osteocalcin Antibody (6F9G4E10) [DyLight 594]
Species: Hu
Applications: ELISA

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Bioinformatics

Gene Symbol BGLAP