Orexin R1/HCRTR1 Antibody - BSA Free

Immunohistochemistry-Paraffin: Orexin R1/HCRTR1 Antibody [NLS6638] - Analysis of anti-HCRTR1 / Orexin Receptor 1 antibody of rat brain, Purkinje neurons at 3.8 ug/ml.

• Reactivity: Hu, Rt, Po, Bv, Rb, Bt, Ca, Pm, Pm
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

Orexin R1/HCRTR1 Antibody - BSA Free Summary

• Description: Product can be stored undiluted at 4C for up to 1 month.
• Immunogen: Synthetic 14 amino acid peptide from 2nd extracellular domain of human Orexin R1/HCRTR1.
• Epitope: 2nd extracellular domain
• Specificity: Human Orexin R1/HCRTR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except HCRTR2 (64%).
• Predicted Species: Primate (100%), Monkey (100%), Canine (93%), Bat (93%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: HCRTR1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 3.8 ug/ml
• Application Notes: .

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (93%), Mouse (86%), Hamster (86%).

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Orexin R1/HCRTR1 Antibody - BSA Free

• HCRTR1
• hypocretin (orexin) receptor 1
• hypocretin receptor 1
• Hypocretin receptor type 1
• hypocretin receptor-1
• Orexin R1
• orexin receptor 1
• orexin receptor type 1
• orexin receptor-1
• OrexinR1
• OX1R
• ox-1-R
• ox1-R

Background

OX1R is an Orexin Receptor selective for orexin A. This receptor participates in the feedback mechanism that regulates feeding behavior and sleep. When activated, OX1R stimulates appetite. OX1R has been implicated in narcolepsy, a sleep/wake disorder. Orexin receptor 1 expression has been documented in adrenal and brain. ESTs have been isolated from brain, pancreas, and lung/spleen libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HCRTR1
• Entrez:
  • 3061(Human)
• Uniprot:
  • O43613(Human)