OCT2 Antibody (Oct2/2136) [Alexa Fluor® 700]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, IHC-P
Clone
Oct2/2136
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 700

OCT2 Antibody (Oct2/2136) [Alexa Fluor® 700] Summary

Immunogen
Recombinant fragment of human OCT2 protein (around aa 112-297) (exact sequence is proprietary)
Localization
Nuclear
Specificity
OCT2 is a transcription factor of the POU homeo-domain family that binds to the Ig gene octamer sites, regulating B-cell-specific genes. OCT2 expression can be used as a marker of B-cell lineage and differentiation. Germinal center B-cells, mantle B-cells, monocytoid B-cells, and plasma cells show high level expression of OCT2. Additionally, mantle cell lymphoma, follicular lymphoma, marginal zone lymphoma, plasmacytoma, Burkitt lymphoma, diffuse large cell lymphoma, diffuse large B-cell lymphoma, Hodgkin lymphoma display increased expression of OCT2. Several studies of OCT2 expression have shown a low level expression in pre-B, T-cell, myelomonocytic, and epithelial cell lines, whereas all mature B-cell lines have high levels of expression. In spite of scanty evidence for OCT2 expression in T cells, it is believed that this factor participates in transcriptional regulation during T-cell activation.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
POU2F2
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for OCT2 Antibody (Oct2/2136) [Alexa Fluor® 700]

  • homeobox protein
  • Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2
  • OCT2Oct-2
  • Octamer-binding protein 2
  • Octamer-binding transcription factor 2
  • OTF-2
  • OTF2POU domain class 2, transcription factor 2
  • POU class 2 homeobox 2
  • POU domain, class 2, transcription factor 2

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-75733AF350
Alexa Fluor 405 NBP2-75733AF405
Alexa Fluor 488 NBP2-75733AF488
Alexa Fluor 532 NBP2-75733AF532
Alexa Fluor 594 NBP2-75733AF594
Alexa Fluor 647 NBP2-75733AF647
Alexa Fluor 700 NBP2-75733AF700
Alexa Fluor 750 NBP2-75733AF750
Biotin NBP2-75733B
DyLight 350 NBP2-75733UV
DyLight 405 NBP2-75733V
DyLight 488 NBP2-75733G
DyLight 550 NBP2-75733R
DyLight 594 NBP2-75733DL594
DyLight 650 NBP2-75733C
DyLight 680 NBP2-75733FR
DyLight 755 NBP2-75733IR
FITC NBP2-75733F
HRP NBP2-75733H
Janelia Fluor 549 NBP2-75733JF549
Janelia Fluor 646 NBP2-75733JF646

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Bioinformatics Tool for OCT2 Antibody (NBP2-75733AF700)

Discover related pathways, diseases and genes to OCT2 Antibody (NBP2-75733AF700). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Blogs on OCT2

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Contact Information

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Calculators

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Bioinformatics

Gene Symbol POU2F2