OCT1 Antibody (YL15)

Product Discontinued

OCT1 Antibody (YL15) Summary

• Immunogen: The immunogen is full length OCT1 protein.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: POU2F1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Gel Super Shift Assays
  • Immunoprecipitation
  • Western Blot

Reactivity Notes

Human, Mouse

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 50% Glycerol
• Preservative: No Preservative
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for OCT1 Antibody (YL15)

• FLJ42836
• NF-A1
• Oct-1
• OCT1class 2, transcription factor 1
• OTF1
• POU class 2 homeobox 1
• POU domain class 2, transcription factor 1
• POU2F1

Background

Oct1 is a transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. It modulates transcription transactivation by NR3C1, AR and PGR and interacts with NR3C1, AR and PGR. Oct1 is Ubiquitous and belongs to the POU transcription factor family class 2 subfamily. Oct1 contains 1 homeobox domain.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for OCT1 Antibody (NBP1-54502)(1)

Publication using NBP1-54502

• Heise M, Lautem A, Knapstein J, Schattenberg JM, Hoppe-Lotichius M, Foltys D, Weiler N, Zimmermann A, Schad A, Grundemann D, Otto G, Galle PR, Schuchmann M, Zimmermann T. Downregulation of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) in human hepatocellular carcinoma and their prognostic significance. BMC Cancer;12:109. 2012-03-22 [PMID: 22439694] (WB, ICC/IF, Human)

Bioinformatics

• Gene Symbol: POU2F1