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NTS1/NTSR1 Antibody

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Immunohistochemistry-Paraffin: Neurotensin Receptor 1 Antibody [NLS939] - Analysis of anti-NTSR1 antibody with human brain, neurons and glia.
Immunohistochemistry-Paraffin: Neurotensin Receptor 1 Antibody [NLS939] - Analysis of anti-NTSR1 antibody with human brain, neurons and glia.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NLS939
    • Availability
      Product Discontinued

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NTS1/NTSR1 Antibody Summary

Immunogen
Synthetic 19 amino acid peptide from C-terminus of human NTS1/NTSR1.
Specificity
Human NTSR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Primate (95%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NTSR1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 52 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (95%), Gibbon (95%), Marmoset (84%), Equine (84%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for NTS1/NTSR1 Antibody

  • NTR
  • NTR1
  • NTRH
  • NTRR
  • NTS1
  • NTSR1

Background

NTR1, a Neurotensin Receptor, activates a phosphatidylinositol-calcium second messenger system in the central and peripheral nervous systems. It mediates the functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion. Neurotensin Receptor 1 expression is enhanced in pancreatic cancer and in chronic pancreatitis (Wang et al, 2000). Two differentially glycosylated forms of the NT1 receptor have been identified in rats, a 54-kDa form that is expressed from birth to adulthood, and a 52-kDa form only detected at 10 and 15 days postnatal. NTR1 has been reported in brain, pancreas, and small intestine. ESTs have been isolated from brain and colon libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol NTSR1
Entrez