NOSTRIN Antibody [Biotin]

• Reactivity: Hu, Mu, Rt, Bv
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Biotin

NOSTRIN Antibody [Biotin] Summary

• Immunogen: NOSTRIN antibody was raised against a 17 amino acid peptide near the carboxy terminus of human NOSTRIN. The immunogen is located within amino acids 430 - 480 of NOSTRIN. Amino Acid Squence: SFQARQDDELNLEKGDI
• Specificity: NOSTRIN antibody is human, mouse and rat reactive. At least four isoforms are known to exist; this antibody will detect all four isoforms.
• Predicted Species: Bovine (94%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: NOSTRIN
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Peptide affinity purified

Alternate Names for NOSTRIN Antibody [Biotin]

• BM247 homolog
• DaIP2
• endothelial nitric oxide synthase traffic inducer
• ENOS traffic inducer
• eNOS-trafficking inducer
• Nitric oxide synthase traffic inducer
• nitric oxide synthase traffickerMGC20702
• nitric oxide synthase trafficking
• nostrin
• ortholog of mouse disabled 2 interacting proein 2

Background

Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NOSTRIN