NMDAR2C Antibody

Western Blot: NMDA R, NR2C Subunit Antibody [H00002905-D01P] - Analysis of GRIN2C expression in transfected 293T cell line by GRIN2C polyclonal antibody.Lane 1: GRIN2C transfected lysate(17.60 KDa).Lane 2: Non-transfected lysate.

Product Discontinued

NMDAR2C Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: GRIN2C (AAH59384.1, 1 a.a. - 171 a.a.) full-length human protein. MGGALGPALLLTSLFGAWAGLGPGQGEQGMTVAVVFSSSGPPQAQFRARLTPQSFLDLPLEIQPLTVGVNTTNPSSLLTQICGLLGAAHVHGIVFEDNVDTEAVAQILDFISSQTHVPILSISGGSAVVLTPKVHVQTHVPSCLRPGTRLGSGVLWFWEAGIRRDGQGGGG
• Specificity: Reacts with glutamate receptor, ionotropic, N-methyl D-aspartate 2C.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GRIN2C
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: This antibody is reactive against transfected lysate in WB and as a detection antibody in ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for NMDAR2C Antibody

• glutamate [NMDA] receptor subunit epsilon-3
• glutamate receptor, ionotropic, N-methyl D-aspartate 2C
• GRIN2C
• NMDA R, NR2C Subunit
• NMDAR2C
• NMDAR2CNR2C
• N-methyl D-aspartate receptor subtype 2C
• N-methyl-D-aspartate receptor subunit 2C
• NR2C

Background

The ion channels activated by glutamate are divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by kainate and a-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid AMPA) are known as kainate/AMPA receptors (K/AMPAR). NMDA receptors are among the most studied receptors in neuroscience because they are involved in neuronal cell development and plasticity, a cellular correlate for learning. NMDA receptors are also implicated in several disorders of the central nervous system including epilepsy and ischemic neuronal cell death. NMDA receptors also appear to be a target for ethanol at physiological concentrations and therefore may play a significant role in alcoholism.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GRIN2C
• Entrez:
  • 2905(Human)
• Uniprot:
  • AAH59384.1(Human)