NKG2E/KLRC3 Antibody - BSA Free

Immunohistochemistry: NKG2E/KLRC3 Antibody [NBP2-46867] - Staining of human tonsil shows strong positivity in a subset of cells.

• Reactivity: Hu
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

NKG2E/KLRC3 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit NKG2E/KLRC3 Antibody - BSA Free (NBP2-46867) is a polyclonal antibody validated for use in IHC. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: NCAMLHVRGLISDQCGSSRIIRRGFIMLTRLVLN
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KLRC3
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  NKG2E/KLRC3 Recombinant Protein Antigen (NBP2-46867PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for NKG2E/KLRC3 Antibody - BSA Free

• killer cell lectin-like receptor subfamily C, member 3
• NK cell receptor E
• NKG2-E type II integral membrane protein
• NKG2E
• NKG2-E-activating NK receptor
• NKG2ENKG2-E

Background

KLRC3 codes for a protein that works as a receptor for the recognition of MHC molecules by natural killers, and in some cases cytotoxic T-cells. KLRC3 is a gene made up of two isoforms, measuring 240 and 257 amino acids in length, and weighing approximately 27 and 29 kDa respectively. Studies have been done on diseases and disorders relating to this gene including monkeypox. KLRC3 has also been shown to have interactions with KLRD1, TYROBP, HLA-A, and HLA-C in pathways such as the antigen processing and natural killer cell mediated cytotoxicity pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KLRC3
• Entrez:
  • 3823(Human)
• Uniprot:
  • Q07444()