NKG2C/CD159c/KLRC2 Antibody (2098A) [FITC]

NKG2C/CD159c/KLRC2 Antibody (2098A) [FITC] [FAB1382F] - Vial of FITC conjugated antibody. FITC is optimally excited at 498 nm by the Blue laser (488 nm) and has an emission maximum of 519 nm.

• Applications: Flow, CyTOF-ready
• Clone: 2098A
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: FITC

NKG2C/CD159c/KLRC2 Antibody (2098A) [FITC] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: Mouse NKG2C/CD159c synthetic peptide
  Accession # NP_034783
• Specificity: Detects mouse NKG2C/CD159c in direct ELISAs. In Flow Cytometry, no cross-reactivity with mouse NKG2A/CD159a is observed.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Purity: Protein A or G purified from cell culture supernatant

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product FAB1382. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from cell culture supernatant

Alternate Names for NKG2C/CD159c/KLRC2 Antibody (2098A) [FITC]

• CD159 antigen-like family member C
• CD159c antigen
• CD159c
• killer cell lectin-like receptor subfamily C, member 2
• KLRC2
• MGC138244
• NK cell receptor C
• NKG2-C type II integral membrane protein
• NKG2C
• NKG2-C
• NKG2CNKG2-C-activating NK receptor

Background

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. KLRC2 alternative splice variants have been described but their full-length nature has not been determined. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.