NKCC1/SLC12A2 Antibody (915911) [Alexa Fluor™ Plus 555]

• Clone: 915911
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 555

NKCC1/SLC12A2 Antibody (915911) [Alexa Fluor™ Plus 555] Summary

• Specificity: Stains NKCC1/SLC12A2 transfectants but not irrelevant transfectants in flow cytometry.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for NKCC1/SLC12A2 Antibody (915911) [Alexa Fluor™ Plus 555]

• Basolateral Na-K-Cl symporter
• BSC
• BSC2
• Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1
• NKCC1
• NKCC1MGC104233
• SLC12A2
• solute carrier family 12 (sodium/potassium/chloride transporters), member 2
• solute carrier family 12 member 2

Background

Solute Carrier, family 12 (potassium/chloride transporter), member 2 (SLC12A2) encodes NKCC1, which mediates sodium and chloride transport and reabsorption. It is a membrane protein that is important in maintaining proper ionic balance and cell volume. In contrast to the renal-specific sodium/potassium/chloride cotransporter SLC12A1, SLC12A2 is expressed in many tissues, including the basolateral membrane of secretory epithelia. It is phosphorylated in response to DNA damage. Three transcript variants encoding two different isoforms have been found for SLC12A2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.