NK3R/TACR3/Neurokinin B Receptor Antibody Blocking Peptide

• Reactivity: Rt
• Applications: AC
• Concentration: 1.0 mg/ml

NK3R/TACR3/Neurokinin B Receptor Antibody Blocking Peptide Summary

• Description: A TACR3 antibody blocking peptide.
• Protein/Peptide Type: Antibody Blocking Peptide
• Gene: TACR3

Applications/Dilutions

• Dilutions:
  • Antibody Competition
• Application Notes: This peptide is useful as a blocking peptide for NB300-102. For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

• Storage: Store at -80C. Avoid freeze-thaw cycles.
• Buffer: Peptide dissolved in dH2O. Contains no BSA.
• Preservative: No Preservative
• Concentration: 1.0 mg/ml

Alternate Names for NK3R/TACR3/Neurokinin B Receptor Antibody Blocking Peptide

• Neurokinin B Receptor
• neurokinin beta receptor
• Neuromedin-K Receptor
• NK-3 receptor
• NK3R
• NK-3R
• NK3RMGC148061
• NKR
• TAC3R
• TAC3RL
• tachykinin receptor 3MGC148060
• TACR3

Background

The Neurokinins, also known as Tachykinins, belong to an evolutionary conserved family of peptide neurotransmitters that share a c-terminal sequence and have an established role in neurotransmission. The mammalian tachykinins include substance P (NK1), neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma.

Three tachykinin receptor types have been characterized, NK-1, NK-2 and NK-3 which have preferential affinities for SP, NKA and NKB respectively. All three receptors share a high degree of sequence homology, have seven transmembrane spanning domains and similar signal transduction mechanisms (e.g. G-protein coupled activation of phospholipase C).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: TACR3