Mu, Rt, GP, Sh, Hu(-)Applications:
ICC/IF, IHC, IHC-Fr, IHC-FrFl, WB (-)Host:
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
The Neurokinins, also known as Tachykinins, belong to an evolutionary conserved family of peptide neurotransmitters that share a c-terminal sequence and have an established role in neurotransmission. The mammalian tachykinins include substance P (NK1), neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma.
Three tachykinin receptor types have been characterized, NK-1, NK-2 and NK-3 which have preferential affinities for SP, NKA and NKB respectively. All three receptors share a high degree of sequence homology, have seven transmembrane spanning domains and similar signal transduction mechanisms (e.g. G-protein coupled activation of phospholipase C).
|Product By Gene ID
- NK-3 receptor
- neuromedin-K receptor
- neurokinin beta receptor
- Neurokinin B receptor
- tachykinin receptor 3MGC148060
Bioinformatics Tool for NK3R/TACR3/Neurokinin B Receptor
Discover related pathways, diseases and genes to NK3R/TACR3/Neurokinin B Receptor. Need help? Read the Bioinformatics Tool Guide
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