NIK/MAP3K14 Antibody [Alexa Fluor™ Plus 594]

• Reactivity: Hu, Mu, Rt, Pm
• Applications: WB, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Alexa Fluor Plus 594

NIK/MAP3K14 Antibody [Alexa Fluor™ Plus 594] Summary

• Immunogen: A synthetic peptide made to a C-terminal portion of the human MAP3K14 protein (between residues 800-900) [UniProt Q99558]
• Localization: Cytoplasmic, nuclear and vesicular.
• Predicted Species: Rat (92%), Primate (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MAP3K14
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Predicted to react with monkey and rat based on sequence homology.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for NIK/MAP3K14 Antibody [Alexa Fluor™ Plus 594]

• EC 2.7.11.25
• FTDCR1B
• HS
• HSNIK
• HSNIKserine/threonine protein-kinase
• MAP3K14
• mitogen-activated protein kinase kinase kinase 14
• NIK
• NIKNF-kappa-beta-inducing kinase
• Serine/threonine-protein kinase NIK

Background

MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14) kinase binds to TRAF2 and stimulates NF-kappaB activity. MAP3K14 is regulated by MAP3K7, RIPK1, TRAF2, TRAF6 and TRAF3. MAP3K14 has been studied in relation to salivary gland cancer, rheumatoid arthritis, t-cell leukemia, ectodermal dysplasia, melanoma and several other diseases and disorders.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MAP3K14