NIK/MAP3K14 Antibody

Western Blot: NIK/MAP3K14 Antibody [NBP1-50748] - Jurkat cell lysate, stained with MAP3K14 Antibody.

Simple Western: NIK/MAP3K14 Antibody [NBP1-50748] - Simple Western lane view shows a specific band for NIK/MAP3K14 in 0.5 mg/ml of Jurkat lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system.

Product Discontinued

NIK/MAP3K14 Antibody Summary

• Immunogen: Synthetic peptide surrounding amino acid 927of human NIK
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MAP3K14
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Simple Western
  • Western Blot 0.5 - 4 ug/mL
• Theoretical MW: 104 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2), 50% glycerol, 1% BSA.
• Preservative: 0.02% Thimerosal
• Concentration: 0.5 mg/ml
• Purity: Affinity purified

Alternate Names for NIK/MAP3K14 Antibody

• EC 2.7.11.25
• FTDCR1B
• HS
• HSNIK
• HSNIKserine/threonine protein-kinase
• MAP3K14
• mitogen-activated protein kinase kinase kinase 14
• NIK
• NIKNF-kappa-beta-inducing kinase
• Serine/threonine-protein kinase NIK

Background

This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: MAP3K14
• Entrez:
  • 9020(Human)
• Uniprot:
  • Q99558()